In some cases, ataxia may be present from birth. Such conditions include Dandy Walker syndrome, Joubert syndrome, Rhombencephalosynapsis and cerebral palsy. In other cases it may develop later in life where it may appear either suddenly or gradually.

Causes of sudden onset ataxia that appears over hours or days include -

Stroke or trauma affecting the cerebellum or associated organs

Bacterial or viral infections of the cerebellum including abscess. Ataxia may occur even after infection due to inflammation, for example after chicken pox infection

Intoxication with alcohol and drugs such as barbiturates and phenytoin

High fever, seizures and migraine. This type of ataxia occurs only during the attack and is called intermittent ataxia

Causes of ataxia that appears over days to weeks include –

Tumours – Tumours can exert pressure on structures important in maintaining balance and coordination

Multiple sclerosis

Intoxication with mercury and some chemotherapy drugs

Lack of vitamin B1 and B12

Lack of vitamin E

AIDS related brain disease

Lyme disease

Causes of ataxia that appears over months to years include -

Inherited disease - Spinocerebellar ataxias, Friedreich’s ataxia, Ataxia telangiectasia, multiple system atrophy, coenzyme Q deficiency, Wilson’s disease, congenital cerebellar ataxia

Low thyroid hormone levels (hypothyroidism)

Tumours - Some tumours like breast, lung and ovarian tumours as well as Hodgkin’s lymphoma can also cause ataxia. In these cases, the body produces some substances called antibodies that damage the cerebellum

Advanced syphilis

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